I’ve made this mayonnaise–Parmesan chicken more times than I can count when I needed a fast, satisfying dinner that feels a little special without the fuss. Tender chicken breasts get a creamy, savory coating that bakes up golden and keeps the meat juicy — perfect for busy weeknights, picky eaters, or when you want something comforting that still looks plated.
If you want a cozy pasta to serve alongside this, try the creamy chicken garlic parmesan pasta recipe for an easy, crowd-pleasing pairing: creamy chicken garlic parmesan pasta.
Why you’ll love this dish
This recipe hits a sweet spot: minimal prep, pantry-friendly ingredients, and reliably juicy chicken. The mayo or Greek yogurt keeps the chicken from drying during the bake and the grated Parmesan adds a salty, slightly nutty crust without needing breadcrumbs. It’s also flexible — swap seasonings, use thicker or thinner breasts, or double the batch for leftovers.
“Simple ingredients, big flavor. The topping makes each bite creamy and golden while keeping the chicken perfectly moist.” — a go-to weeknight favorite from my kitchen
This is ideal for weeknight dinners, easy dinner parties, or meal prep days when you want protein that reheats well. Parents like it because it’s mild and familiar; home cooks like it because it’s forgiving.
Step-by-step overview
You’ll preheat and prep the pan, pound the breasts for even cooking, whisk a quick mayo-Parmesan mixture, spread it over the chicken, and bake until done. Expect about 10 minutes of active prep and 35 to 45 minutes in the oven depending on thickness. Finish with a brief rest, slice, and serve.
What you’ll need
- 4 boneless, skinless chicken breasts
- 1 cup mayonnaise or plain Greek yogurt (use yogurt for tang and fewer calories)
- 1/2 cup grated Parmesan cheese (freshly grated gives the best texture)
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- 1 teaspoon salt
- 1/2 teaspoon black pepper
- Optional: 1/2 teaspoon paprika or Italian seasoning
Notes on ingredients and substitutions:
- Mayonnaise gives a richer, creamier crust; plain Greek yogurt yields a tangier, lighter finish. Either works well.
- Freshly grated Parmesan melts and browns better than pre-shredded blends that contain anti-caking agents.
- If breasts are large, halve them horizontally to get four even pieces or pound until about 3/4 inch thick for uniform cooking.
Step-by-step instructions
- Preheat the oven to 375°F (190°C). Grease a 9×13-inch baking dish.
- Place each chicken breast between two sheets of plastic wrap. Pound gently with a meat mallet or rolling pin until the thickness is about 3/4 inch. This helps the chicken cook evenly.
- In a medium bowl, whisk together the mayonnaise or yogurt, Parmesan, garlic powder, onion powder, salt, and black pepper until smooth.
- Spread the mixture evenly over the top of each chicken breast so there’s a uniform coating.
- Arrange the coated breasts in the prepared dish. Sprinkle with the optional paprika or Italian seasoning for color and extra flavor.
- Bake uncovered for 35 to 45 minutes, or until the chicken reaches an internal temperature of 165°F (74°C) and the topping is lightly golden. Use an instant-read thermometer in the thickest part to be sure.
- Remove from the oven and let the chicken rest for 5 minutes before slicing and serving.

Best ways to enjoy it
This chicken is very adaptable. Serve it over buttery mashed potatoes, alongside steamed green beans and a lemon wedge, or on a bed of mixed greens for a lighter meal. For a weeknight combo that kids and adults both like, slice and tuck into warmed tortillas with shredded lettuce and a squeeze of lemon.
For a completely different flavor day, pair this with an Indian-style main as part of a varied menu; try the authentic butter chicken recipe for another richly sauced option: authentic butter chicken recipe.
Storage and reheating tips
Refrigerate leftovers in an airtight container within two hours of cooking. Keep for up to 3 to 4 days. To reheat, warm gently in a 350°F (175°C) oven covered with foil for 10 to 15 minutes, or microwave in 30-second bursts until heated through. To freeze, wrap each breast tightly or store in a freezer-safe container for up to 3 months; thaw overnight in the refrigerator before reheating. Always confirm the internal temperature reaches 165°F (74°C) when reheating.
Helpful cooking tips
- Pound to an even thickness: this reduces overcooking and keeps all pieces tender.
- Room temperature chicken reduces oven time variance. Let breasts sit out 15 minutes before baking.
- If you want extra browning, switch the oven to broil for the last 1 to 2 minutes while watching closely.
- Use an instant-read thermometer for safety and perfect doneness — 165°F (74°C) in the thickest part.
- If using Greek yogurt, stir a teaspoon of olive oil into the mixture to help browning and sheen.
Recipe variations
- Mediterranean twist: add 1 tablespoon chopped fresh parsley, 1 teaspoon lemon zest, and swap paprika for oregano.
- Spicy version: fold 1/2 teaspoon cayenne or a pinch of red pepper flakes into the mayo mixture.
- Gluten-free crunchy top: mix 1/4 cup crushed gluten-free crackers with the Parmesan and sprinkle on top for texture.
- Herb-forward: stir 1 tablespoon chopped basil and 1 tablespoon chopped chives into the topping before spreading.
Helpful answers
How long does this take from start to finish?
Active prep is about 10 minutes. Baking takes 35 to 45 minutes depending on thickness. Allow 5 minutes to rest before serving. Plan for about 50 to 60 minutes total.
Can I use bone-in chicken or thighs instead of breasts?
Yes, but adjust cooking time. Bone-in pieces generally need longer in the oven; check with a thermometer and aim for 165°F (74°C) near the bone. Thighs stay juicier and may require less time if boneless.
Is Greek yogurt really interchangeable with mayonnaise?
Yes. Greek yogurt makes the topping tangier and lighter while mayonnaise gives a richer, creamier crust. Use whichever suits your taste or dietary needs; both protect the chicken from drying out.
How do I know when it’s done without a thermometer?
Take the safest route and use an instant-read thermometer. If you don’t have one, pierce the thickest part: juices should run clear and the meat should be opaque with no pink. But a thermometer is the most reliable method.
Can I make this ahead for a party?
You can assemble the chicken in the baking dish, cover, and refrigerate for up to 24 hours before baking. Bring it to room temperature for 15 minutes before baking and increase bake time slightly if chilled.

Mayonnaise-Parmesan Chicken
Ingredients
Method
- Preheat the oven to 375°F (190°C). Grease a 9x13-inch baking dish.
- Place each chicken breast between two sheets of plastic wrap. Pound gently with a meat mallet or rolling pin until the thickness is about 3/4 inch.
- In a medium bowl, whisk together the mayonnaise or yogurt, Parmesan, garlic powder, onion powder, salt, and black pepper until smooth.
- Spread the mixture evenly over the top of each chicken breast.
- Arrange the coated breasts in the prepared dish and sprinkle with optional paprika or Italian seasoning.
- Bake uncovered for 35 to 45 minutes, until the chicken reaches an internal temperature of 165°F (74°C) and the topping is lightly golden.
- Remove from the oven and let the chicken rest for 5 minutes before slicing and serving.


